HYPONEOPHAGIA IN WISTAR-KYOTO (WKY) RATS

被引：38

作者：

PARE, WP ^{[1
]}

机构：

[1] UNIV PENN, DEPT PSYCHIAT, PHILADELPHIA, PA 19104 USA

来源：

PHYSIOLOGY & BEHAVIOR | 1994年 / 55卷 / 05期

关键词：

DEPRESSION; HYPONEOPHAGIA; FEEDING SUPPRESSION; WKY RAT; STRAIN DIFFERENCES; ANIMAL MODELS; STRESS; NOVELTY;

D O I：

10.1016/0031-9384(94)90090-6

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Unconditioned suppression of feeding due to novelty (hyponeophagia) was studied in Wistar Kyoto (WKY), Lewis, Fischer 344, and Wistar rats. Fasted rats were given access to food either in home cages (controls) or to a single pellet fixed to the middle of a novel open field environment (experimental). The degree of feeding suppression was significantly greater in WKY rats compared to the other three strains. We suggest that this hyponeophagia resembles the reduced feeding frequently associated with behavioral depression, and that this behavior in WKY rats is another demonstration that this strain is very responsive to stressful stimulation and may serve as a useful animal model for depressive behavior.

引用

页码：975 / 978

页数：4

共 25 条

[1] EXPERIMENTS ON NEOPHOBIA IN WILD AND LABORATORY RATS [J].