URINE CONCENTRATING ABILITY AFTER PROLONGED SEVOFLURANE ANESTHESIA

被引:24
作者
HIGUCHI, H [1 ]
ARIMURA, S [1 ]
SUMIKURA, H [1 ]
SATOH, T [1 ]
KANNO, M [1 ]
机构
[1] CENT HOSP SELF DEF FORCE,DEPT ANAESTHESIA,TOKYO,JAPAN
关键词
ANESTHETICS; VOLATILE; SEVOFLURANE; ANESTHETICS VOLATILE; ISOFLURANE; TOXICITY;
D O I
10.1093/bja/73.2.239
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Few studies have used the vasopressin test to evaluate urine concentrating ability after sevoflurane anaesthesia. We performed a vasopressin test on the first day after operation to compare the effect of prolonged sevoflurane anaesthesia for orthopaedic procedures (n = 11) with that of isoflurane (n = 10). Mean doses of sevoflurane and isoflurane were 10.6 (SE 0.9) and 8.5 (1.5) MAC-h, respectively. Mean peak serum fluoride concentration in patients anaesthetized with sevoflurane was 41.9 (2.5) mu mol litre(-1) and exceeded 20 mu mol litre(-1) for approximately 20 h. Each group showed similar responses 50 vasopressin. There was no evidence of sub clinical nephrotoxicity in patients given prolonged sevoflurane anaesthesia.
引用
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页码:239 / 240
页数:2
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