ANGIOEDEMA ASSOCIATED WITH LISINOPRIL

被引:21
作者
REES, RS
BERGMAN, J
RAMIREZALEXANDER, R
机构
[1] Department of Medicine, New York, NY
[2] Department of Ambulatory Care, New York, NY
[3] the Department of Veterans Affairs Medical Center, New York, NY
[4] the NYU School of Medicine, New York, NY
关键词
ANGIOEDEMA; LISINOPRIL; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS;
D O I
10.1016/0735-6757(92)90010-U
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Angioedema has been reported to occur in association with all angiotensin-converting enzyme inhibitors used in the United States. We reviewed nine cases of angioedema associated with lisinopril use seen in the emergency department at our hospital among 1,970 patients that had been prescribed lisinopril from March 1989 to May 1990. Cases were considered as probably (six cases) or possibly (three cases) drug related, depending on the temporal relationship of the initiation of therapy and the onset of angioedema. All of the cases had edema of the lips, buccal mucosa, and or face. None presented with laryngeal edema or stridor. The angioedema resolved within 1 to 2 days with diphenhydramine treatment and discontinuation of lisinopril. Our data suggest that the incidence of angioedema associated with lisinopril is greater than that associated with captopril or enalapril. © 1992.
引用
收藏
页码:321 / 322
页数:2
相关论文
共 11 条
[1]  
Gianos, Klaustermeyer, Kurohara, Et al., Enalapril induced angioedema, Am J Emerg Med, 8, pp. 124-126, (1990)
[2]  
Chin, Buchan, Severe angioedema after long-term use of an angiotensin-converting enzyme inhibitor, Ann Intern Med, 112, pp. 312-313, (1990)
[3]  
US Physicians Desk Reference, (1990)
[4]  
US Physicians Desk Reference, (1990)
[5]  
Slater, Merrill, Guess, Et al., Clinical profile of angioedema associated with angiotensin converting-enzyme inhibition, JAMA, 260, pp. 967-970, (1988)
[6]  
Irvin, Viau, Safety profiles of the angiotensin converting enzyme inhibitors captopril and enalapril, Am J Med, 81, 4 C, pp. 46-50, (1986)
[7]  
Singer, Macgregor, Angioneurotic oedema associated with two angiotensin converting enzyme inhibitors, Br Med J, 293, (1986)
[8]  
Cameron, Higgins, Clinical experience with lisinopril. Observations on safety and tolerability, J Hum Hypertens, 3, 1, pp. 177-186, (1989)
[9]  
Wood, Mann, Rawlins, Angio-oedema and urticaria associated with angiotensin converting enzyme inhibitors, Br Med J, 294, pp. 91-92, (1987)
[10]  
Ferner, Simpson, Rawlins, Effects of intradermal bradykinin after inhibition of angiotensin converting enzyme, Br Med J, 294, pp. 1119-1120, (1987)