THE C-ELEGANS GENOME SEQUENCING PROJECT - A BEGINNING

被引：465

作者：

SULSTON, J

DU, Z

THOMAS, K

WILSON, R

HILLIER, L

STADEN, R

HALLORAN, N

GREEN, P

THIERRYMIEG, J

QIU, L

DEAR, S

COULSON, A

CRAXTON, M

DURBIN, R

BERKS, M

METZSTEIN, M

HAWKINS, T

AINSCOUGH, R

WATERSTON, R

机构：

[1] WASHINGTON UNIV,SCH MED,DEPT GENET,ST LOUIS,MO 63110

[2] CTR RECH BIOCHIM MACROMOLEC & PHYS MATH,CNRS,F-34044 MONTPELLIER,FRANCE

来源：

NATURE | 1992年 / 356卷 / 6364期

关键词：

D O I：

10.1038/356037a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisingly rich in genes, many of which have mammalian homologues.

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页码：37 / 41

页数：5

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