POINT MUTATIONS CAUSE THE SOMATIC DIVERSIFICATION OF IGM AND IGG2A ANTIPHOSPHORYLCHOLINE ANTIBODIES

被引：72

作者：

CHIEN, NC ^{[1
]}

POLLOCK, RR ^{[1
]}

DESAYMARD, C ^{[1
]}

SCHARFF, MD ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,IRVINGTON HOUSE INST,BRONX,NY 10461

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 1988年 / 167卷 / 03期

关键词：

D O I：

10.1084/jem.167.3.954

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：954 / 973

页数：20

共 60 条

[1] ANTIBODY DIVERSITY - NEW MECHANISM REVEALED [J].

ALT, FW .

NATURE, 1986, 322 (6082) :772-773

[2] ORDERED REARRANGEMENT OF IMMUNOGLOBULIN HEAVY-CHAIN VARIABLE REGION SEGMENTS [J].

ALT, FW ;

YANCOPOULOS, GD ;

BLACKWELL, TK ;

WOOD, C ;

THOMAS, E ;

BOSS, M ;

COFFMAN, R ;

ROSENBERG, N ;

TONEGAWA, S ;

BALTIMORE, D .

EMBO JOURNAL, 1984, 3 (06) :1209-1219

[3] 3-DIMENSIONAL STRUCTURE OF AN ANTIGEN-ANTIBODY COMPLEX AT 2.8-A RESOLUTION [J].

AMIT, AG ;

MARIUZZA, RA ;

PHILLIPS, SEV ;

POLJAK, RJ .

SCIENCE, 1986, 233 (4765) :747-753

[4] SEQUENCE HOMOLOGY REQUIREMENTS FOR INTERMOLECULAR RECOMBINATION IN MAMMALIAN-CELLS [J].

AYARES, D ;

CHEKURI, L ;

SONG, KY ;

KUCHERLAPATI, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (14) :5199-5203

[5] PHOSPHORYLCHOLINE-BINDING HYBRIDOMA PROTEINS OF NORMAL AND IDIOTYPICALLY SUPPRESSED BALB-C MICE .1. CHARACTERIZATION AND IDIOTYPIC ANALYSIS [J].

BEREK, C ;

SCHREIER, MH ;

SIDMAN, CL ;

JATON, JC ;

KOCHER, HP ;

COSENZA, H .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1980, 10 (04) :258-263

[6] MUTATION DRIFT AND REPERTOIRE SHIFT IN THE MATURATION OF THE IMMUNE-RESPONSE [J].

BEREK, C ;

MILSTEIN, C .

IMMUNOLOGICAL REVIEWS, 1987, 96 :23-41

[7]

BOTHWELL MA, 1978, J BIOL CHEM, V253, P2073

[8]

CHANG SP, 1984, J IMMUNOL, V132, P1550

[9]

CHESEBRO B, 1972, BIOCHEMISTRY-US, V11, P766, DOI 10.1021/bi00755a014

[10] ISOLATION OF BIOLOGICALLY-ACTIVE RIBONUCLEIC-ACID FROM SOURCES ENRICHED IN RIBONUCLEASE [J].

CHIRGWIN, JM ;

PRZYBYLA, AE ;

MACDONALD, RJ ;

RUTTER, WJ .

BIOCHEMISTRY, 1979, 18 (24) :5294-5299

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