CONTRIBUTION OF RENAL BIOPSY DATA IN PREDICTING OUTCOME IN LUPUS NEPHRITIS - ANALYSIS OF 116 PATIENTS

被引：138

作者：

NOSSENT, HC

HENZENLOGMANS, SC

VROOM, TM

BERDEN, JHM

SWAAK, TJG

机构：

[1] DR DANIEL DEN HOED CLIN,DEPT PATHOL,ROTTERDAM,NETHERLANDS

[2] SLOTERVAART HOSP,DEPT PATHOL,AMSTERDAM,NETHERLANDS

[3] CATHOLIC UNIV NIJMEGEN,ST RADBOUD HOSP,DEPT NEPHROL,NIJMEGEN,NETHERLANDS

来源：

ARTHRITIS AND RHEUMATISM | 1990年 / 33卷 / 07期

关键词：

D O I：

10.1002/art.1780330708

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We reassessed renal biopsy specimens from 116 patients with systemic lupus erythematosus and clinical manifestations of lupus nephritis to determine the contributions of the World Health Organization classification system, the activity and chronicity indexes of the National Institutes of Health scoring system, and various clinical parameters at the time of biopsy to predicting disease outcome. Multivariate analysis showed that only a chronicity index >3 was predictive for decreased renal survival, while age >31 years at biopsy and a chronicity index >3 were associated with decreased patient survival. Clinical tests of renal function were not reliable in discriminating between active lesions and chronic renal damage. Copyright © 1990 American College of Rheumatology

引用

页码：970 / 977

页数：8

共 37 条

[1] PROGNOSTIC FACTORS IN LUPUS NEPHRITIS - CONTRIBUTION OF RENAL HISTOLOGIC DATA [J].