ABSENCE OF BRAIN SPECIFIC BENZODIAZEPINE RECEPTORS IN CYCLOSTOMES AND ELASMOBRANCHS

被引：14

作者：

FERNHOLM, B ^{[1
]}

NIELSEN, M ^{[1
]}

BRAESTRUP, C ^{[1
]}

机构：

[1] ST HANS MENTAL HOSP,PSYCHOPHARMACOL RES LAB,DK-4000 ROSKILDE,DENMARK

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1979年 / 62卷 / 02期

关键词：

D O I：

10.1016/0306-4492(79)90012-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Specific (3H)-diazepam receptor binding was not detectable in brains of Myxine glutinosa, Lampetra fluviatilis, Squalus acanthias and Chimaera monstrosa, while readily detectable in Calamoichthys calabaricus, Acipenser ruthenus, Salmo salar and Gadus morhua. 2. Opiate receptors, in contrast, were found in all investigated species. 3. These results indicate that the evolution of benzodiazepine receptors in the brain occurred only in those ancestral fishes giving rise to higher bony fishes and tetrapods. © 1979.

引用

页码：209 / 211

页数：3

共 13 条

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