A STUDY OF THE BINDING OF VANCOMYCIN TO DIPEPTIDES USING CAPILLARY ELECTROPHORESIS

被引:62
作者
CARPENTER, JL
CAMILLERI, P
DHANAK, D
GOODALL, D
机构
[1] SMITHKLINE BEECHAM,THE FRYTHE,WELWYN GARDEN CIT AL6 9AR,HERTS,ENGLAND
[2] UNIV YORK,DEPT CHEM,YORK YO1 5DD,N YORKSHIRE,ENGLAND
关键词
D O I
10.1039/c39920000804
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Capillary electrophoresis (CE) has been used as a rapid technique for the determination of the absolute binding constants of dipeptides with vancomycin in solution; the values obtained for the mucopeptide mimic N-acetyl-D-Ala-D-Ala and related dipeptides are in good agreement with values reported in the literature using either differential UV spectrometry or NMR.
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页码:804 / 806
页数:3
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