A CONVENIENT SYNTHESIS OF A SIMPLE COUMARIN FROM SALICYLALDEHYDE AND WITTIG REAGENT .1. A SYNTHESIS OF METHOXYCOUMARIN AND HYDROXYCOUMARIN

被引：33

作者：

HARAYAMA, T ^{[1
]}

KATSUNO, K ^{[1
]}

NISHIOKA, H ^{[1
]}

FUJII, M ^{[1
]}

NISHITA, Y ^{[1
]}

ISHII, H ^{[1
]}

KANEKO, Y ^{[1
]}

机构：

[1] CHIBA UNIV,FAC PHARMACEUT SCI,INAGE KU,CHIBA 263,JAPAN

来源：

HETEROCYCLES | 1994年 / 39卷 / 02期

关键词：

D O I：

10.3987/COM-94-S(B)54

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of methoxy- and hydroxysalicylaldehydes (1) with phosphorane in diethylaniline under reflux gave only coumarins (3) in high yields except for 3-methoxysalicylaldehyde (1b). It was clarified that methoxy group(s) at C-4 and C-6 on 1 facilitated the formation of 3.

引用

页码：613 / 622

页数：10

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