3,5-DINITROSALICYLIC ACID(5-NITROFURFURYLIDENE)HYDRAZIDE A POTENT NEW PREVENTIVE OF HISTOMONIASIS IN TURKEYS

被引：10

作者：

BERNDT, EW

VANESSEN, H

HELD, BG

VATNE, RD

机构：

[1] Research Division, Salsbury Laboratories, Charles City

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 03期

关键词：

D O I：

10.1021/jm00303a006

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of substituted benzoic acid (5-nitrofurfurylidene)hydrazides has been prepared and screened extensively for antibacterial and antiprotozoal activity. One of these compounds, 3,5-dinitrosalicylic acid (5-nitrofurfurylidene)hydrazide (I), has shown outstanding antihistomonal activity in poultry. The related compounds that have been synthesized and their test results in preventing blackhead disease in turkeys are presented. Possible reasons for the high degree of activity and specificity of I are discussed. © 1969, American Chemical Society. All rights reserved.

引用

页码：371 / &

共 13 条

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