DATA-BANK OF 3-DIMENSIONAL STRUCTURES OF DISACCHARIDES, A TOOL TO BUILD 3-D STRUCTURES OF OLIGOSACCHARIDES .1. OLIGO-MANNOSE TYPE N-GLYCANS

被引：81

作者：

IMBERTY, A

GERBER, S

TRAN, V

PEREZ, S

机构：

[1] Laboratoire de Physicochimie des Macromolécules, INRA, Nantes, Cedex 03, 44026

来源：

GLYCOCONJUGATE JOURNAL | 1990年 / 7卷 / 01期

关键词：

modeling; oligosaccharide; three dimensional structure;

D O I：

10.1007/BF01050401

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This work presents the first part of a database of conformations for all the disaccharide fragments that are found in N-glycans. The conformational study of the five disaccharides found in the oligo-mannose type are presented here. For each disaccharide, several possible conformations are described. A method is presented to obtain realistic models of oligosaccharides using molecular mechanic methods. Analysis of some possible conformations of the oligo-mannose type glycan Man6-GlcNAc2 is given as an illustration of the possibilities. © 1990 Glycoconjugate Journal.

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页码：27 / 54

页数：28

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