LORAZEPAM VS ALPRAZOLAM IN THE TREATMENT OF PANIC DISORDER

被引：45

作者：

SCHWEIZER, E ^{[1
]}

POHL, R ^{[1
]}

BALON, R ^{[1
]}

FOX, I ^{[1
]}

RICKELS, K ^{[1
]}

YERAGANI, VK ^{[1
]}

机构：

[1] WAYNE STATE UNIV,LAFAYETTE CLIN,DETROIT,MI 48202

来源：

PHARMACOPSYCHIATRY | 1990年 / 23卷 / 02期

关键词：

D O I：

10.1055/s-2007-1014489

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Sixty-seven patients with panic disorder were treated with single-blind placebo for one week before being randomized to 6 weeks of double-blind treatment with either lorazepam or alprazolam. Both drugs showed significant and comparable antipanic efficacy throughout the course of the study. With the exception of sedative effects, both drugs were well-tolerated at a mean daily dose of 7 mg for lorazepam and 3 mg for alprazolam. Lorazepam appeared to be as effective as alprozolam in the acute treatment of panic disorder.

引用

页码：90 / 93

页数：4

共 11 条

[1]

BALLENGER JC, 1988, ARCH GEN PSYCHIAT, V45, P413

[2]

BEAUDRY P, 1986, J CLIN PSYCHIAT, V47, P83

[3]

CHARNEY DS, 1986, J CLIN PSYCHIAT, V47, P580

[4] ALPRAZOLAM IN THE TREATMENT OF GENERALIZED ANXIETY AND PANIC DISORDERS - A DOUBLE-BLIND PLACEBO-CONTROLLED STUDY [J].