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GENES FOR TRYPTOPHAN BIOSYNTHESIS IN THE ARCHAEBACTERIUM HALOFERAX-VOLCANII

被引：32
作者：
LAM, WL
COHEN, A
TSOULUHAS, D
DOOLITTLE, WF
机构：
[1] Department of Biochemistry, Dalhousie University, Halifax
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1990年 / 87卷 / 17期
关键词：
Evolution; Genetic mapping; Halobacterium; Indole-3-glycerol-phosphate synthase; Tryptophan synthase;
D O I：
10.1073/pnas.87.17.6614
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Recent technical advances permit direct genetic approaches for isolating genes and mapping auxotrophic mutations in the halophilic archaebacterium (Archaea) Haloferax volcanii. Twenty-nine mutations in tryptophan biosynthesis mapped to two separate chromosomal locations. DNA sequencing of one gene cluster shows a unique gene order (trpCBA) and unusual potential secondary structures in the 5′-flanking region.
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页码：6614 / 6618
页数：5
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