RAPID GROWTH OF LEIOMYOMA IN PATIENT RECEIVING TAMOXIFEN

被引：67

作者：

DILTS, PV

HOPKINS, MP

CHANG, AE

CODY, RL

机构：

[1] UNIV MICHIGAN,MED CTR,DEPT SURG,ANN ARBOR,MI 48109

[2] UNIV MICHIGAN,MED CTR,DEPT INTERNAL MED,ANN ARBOR,MI 48109

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1992年 / 166卷 / 01期

关键词：

TAMOXIFEN; LEIOMYOMA;

D O I：

10.1016/0002-9378(92)91854-4

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A 49-year-old patient with breast cancer had a leiomyoma that rapidly enlarged shortly after she started therapy with tamoxifen. Exploratory laparotomy was necessary to confirm the diagnosis. The rapid growth may have resulted from the estrogen agonist properties of tamoxifen or alternatively by ovarian stimulation resulting in endogenous estrogen production.

引用

页码：167 / 168

页数：2

共 3 条

[1] A RANDOMIZED CLINICAL-TRIAL EVALUATING TAMOXIFEN IN THE TREATMENT OF PATIENTS WITH NODE-NEGATIVE BREAST-CANCER WHO HAVE ESTROGEN-RECEPTOR POSITIVE TUMORS
FISHER, B
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DIMITROV, NV
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[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (08) : 479 - 484
[2] TAMOXIFEN PROLONGS LUTEAL PHASE IN PREMENOPAUSAL WOMEN BUT HAS NO EFFECT ON THE SIZE OF UTERINE FIBROIDS
LUMSDEN, MA
WEST, CP
BAIRD, DT
[J]. CLINICAL ENDOCRINOLOGY, 1989, 31 (03) : 335 - 343
[3] PHARMACODYNAMIC AND BIOLOGICAL EFFECTS OF ANTI-ESTROGENS IN DIFFERENT MODELS
PASQUALINI, JR
SUMIDA, C
GIAMBIAGI, N
[J]. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1988, 31 (4B) : 613 - 643

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