STUDIES ON THE EFFECTS OF L-ASCORBIC-ACID ON ACETAMINOPHEN-INDUCED HEPATOTOXICITY .1. INHIBITION OF THE COVALENT BINDING OF ACETAMINOPHEN METABOLITES TO HEPATIC MICROSOMES INVITRO

被引：42

作者：

LAKE, BG

HARRIS, RA

PHILLIPS, JC

GANGOLLI, SD

机构：

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1981年 / 60卷 / 02期

关键词：

D O I：

10.1016/0041-008X(91)90227-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：229 / 240

页数：12

共 60 条

[1]

AIKAWA K, 1977, BIOCHEM PHARMACOL, V26, P893

[2] LIVER NECROSIS FROM PARACETAMOL [J].

BOYD, EM ;

BERECZKY, GM .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1966, 26 (03) :606-&

[3] VARYING EFFECTS OF SULFHYDRYL NUCLEOPHILES ON ACETAMINOPHEN OXIDATION AND SULFHYDRYL ADDUCT FORMATION [J].

BUCKPITT, AR ;

ROLLINS, DE ;

MITCHELL, JR .

BIOCHEMICAL PHARMACOLOGY, 1979, 28 (19) :2941-2946

[4]

BYE HE, 1979, PHARM J, V223, P407

[5]

CLARK R, 1973, LANCET, V1, P66

[6]

COLDWELL BB, 1976, P EUROPEAN SOC TOXIC, V17, P269

[7]

CORCORAN GB, 1980, MOL PHARMACOL, V18, P536

[8]

CROME P, 1976, LANCET, V2, P829

[9] SPECIES-DIFFERENCES IN HEPATIC GLUTATHIONE DEPLETION, COVALENT BINDING AND HEPATIC NECROSIS AFTER ACETAMINOPHEN [J].

DAVIS, DC ;

POTTER, WZ ;

JOLLOW, DJ ;

MITCHELL, JR .

LIFE SCIENCES, 1974, 14 (11) :2099-2109

[10]

DEAMER DW, 1971, PHYSIOL CHEM PHYS M, V3, P426

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