RADIATION-INDUCED GLIOSARCOMA - CASE-REPORT AND REVIEW OF THE LITERATURE

被引：65

作者：

KASCHTEN, B

FLANDROY, P

REZNIK, M

HAINAUT, H

STEVENAERT, A

机构：

[1] UNIV LIEGE HOSP,DEPT NEUROSURG,LIEGE,BELGIUM

[2] UNIV LIEGE HOSP,DEPT NEURORADIOL,LIEGE,BELGIUM

[3] UNIV LIEGE HOSP,DEPT NEUROPATHOL,LIEGE,BELGIUM

[4] CTR HOSP ST JOSEPH ESPERANCE,DEPT PEDIAT,LIEGE,BELGIUM

来源：

JOURNAL OF NEUROSURGERY | 1995年 / 83卷 / 01期

关键词：

RADIATION-INDUCED TUMOR; BRAIN NEOPLASM; GLIOMA; GLIOSARCOMA; ACUTE LYMPHOBLASTIC LEUKEMIA;

D O I：

10.3171/jns.1995.83.1.0154

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 13-year-old boy presented with a cerebral gliosarcoma 12 years after having acute lymphoblastic leukemia treated by chemotherapy and central nervous system prophylaxis treated by radiation therapy (24 Gy) and intrathecal methotrexate. A review of the literature disclosed 129 possible radiation-induced gliomatous and/or sarcomatous brain tumors: namely, 89 gliomas, 36 sarcomas, and four gliosarcomas, including the present case. An analysis of these cases revealed several characteristics that differentiate them from similar spontaneous brain tumors, thus providing arguments for the carcinogenic effect of radiation therapy on intracranial tumors.

引用

页码：154 / 162

页数：9

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