NOVEL EXTRACELLULAR MYCOBACTINS, THE CARBOXYMYCOBACTINS FROM MYCOBACTERIUM-AVIUM

被引：42

作者：

LANE, SJ ^{[1
]}

MARSHALL, PS ^{[1
]}

UPTON, RJ ^{[1
]}

RATLEDGE, C ^{[1
]}

EWING, M ^{[1
]}

机构：

[1] UNIV HULL,DEPT APPL BIOL,KINGSTON HULL HU6 7RX,N HUMBERSIDE,ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 23期

关键词：

D O I：

10.1016/0040-4039(95)00676-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel extracellular siderophores, termed carboxymycobactins, have been isolated from M. avium as iron complexes and their structures determined. They are the first extracellular siderophores to be characterised from pathogenic mycobacteria and are analogous to their intracellular mycobactin counterparts, except that their R(1) alkyl sidechain is shorter and terminates in a carboxylic acid, resulting in much greater hydrophilicity and explaining their occurrence in the aqueous extracellular medium.

引用

页码：4129 / 4132

页数：4

共 8 条

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