PYRIDAZINYL-GABA DERIVATIVES - A NEW CLASS OF SYNTHETIC GABA-A ANTAGONISTS

被引：61

作者：

WERMUTH, CG ^{[1
]}

BIZIERE, K ^{[1
]}

机构：

[1] SANOFI RECH,CTR RECH CLIN MIDY,DEPT NEUROBIOL,F-34082 MONTPELLIER,FRANCE

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1986年 / 7卷 / 11期

关键词：

D O I：

10.1016/0165-6147(86)90408-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：421 / 424

页数：4

共 28 条

[1] ISOTHIOURONIUM COMPOUNDS AS GAMMA-AMINOBUTYRIC-ACID AGONISTS [J].

ALLAN, RD ;

DICKENSON, HW ;

HIERN, BP ;

JOHNSTON, GAR ;

KAZLAUSKAS, R .

BRITISH JOURNAL OF PHARMACOLOGY, 1986, 88 (02) :379-387

[2] SECURININE ALKALOIDS - A NEW CLASS OF GABA RECEPTOR ANTAGONIST [J].

BEUTLER, JA ;

KARBON, EW ;

BRUBAKER, AN ;

MALIK, R ;

CURTIS, DR ;

ENNA, SJ .

BRAIN RESEARCH, 1985, 330 (01) :135-140

[3]

BOURGUIGNON JJ, J MED CHEM

[4]

BOURGUIGNON JJ, 1985, PHARMACOLOGIST, V27, P518

[5]

BRECKENRIDGE RJ, 1981, J NEUROCHEM, V37, P837, DOI 10.1111/j.1471-4159.1981.tb04469.x

[6] AN ARYLAMINOPYRIDAZINE DERIVATIVE OF GAMMA-AMINOBUTYRIC ACID (GABA) IS A SELECTIVE AND COMPETITIVE ANTAGONIST AT THE GABAA RECEPTOR-SITE [J].

CHAMBON, JP ;

FELTZ, P ;

HEAULME, M ;

RESTLE, S ;

SCHLICHTER, R ;

BIZIERE, K ;

WERMUTH, CG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (06) :1832-1836

[7] (+) AND (-)-BICUCULLINE METHOCHLORIDE AS OPTICAL ISOMERS OF A GABA ANTAGONIST [J].

COLLINS, JF ;

HILL, RG .

NATURE, 1974, 249 (5460) :845-847

[8] GABA, BICUCULLINE AND CENTRAL INHIBITION [J].

CURTIS, DR ;

DUGGAN, AW ;

FELIX, D ;

JOHNSTON, GA .

NATURE, 1970, 226 (5252) :1222-&

[9]

DESARMENIEN M, BR J PHARM

[10]

FALCH E, 1985, EUR J MED CHEM, V20, P447

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