VASOACTIVE INTESTINAL POLYPEPTIDE - RELEASE INTO HYPOPHYSEAL PORTAL BLOOD

被引：245

作者：

SAID, SI

PORTER, JC

机构：

[1] UNIV TEXAS,SW MED SCH,DEPT OBSTET & GYNECOL,DALLAS,TX 75235

[2] UNIV TEXAS,SW MED SCH,DEPT PHARMACOL,DALLAS,TX 75235

[3] UNIV TEXAS,SW MED SCH,DEPT INTERNAL MED,DALLAS,TX 75235

[4] UNIV TEXAS,SW MED SCH,DEPT PHYSIOL,DALLAS,TX 75235

来源：

LIFE SCIENCES | 1979年 / 24卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0024-3205(79)90223-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Immunoreactive vasoactive intestinal polypeptide (VIP) was present in portal hypophyseal blood of 24 male rats in concentrations (mean, 995 pg per ml) that were approximately 19 times as high as those in systemic arterial blood (mean, 52 pg per ml). The results demonstrate release of VIP from the hypothalamic-neurohypophyseal complex into the portal circulation, and establish a mechanism for direct influence of the peptide on pituitary function. © 1979.

引用

页码：227 / 230

页数：4

共 21 条

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[5] VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) - VESICULAR LOCALIZATION AND POTASSIUM EVOKED RELEASE FROM RAT HYPOTHALAMUS
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IVERSEN, LL
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[6] VASOACTIVE INTESTINAL POLYPEPTIDE AND NERVOUS-SYSTEM - IMMUNOHISTOCHEMICAL EVIDENCE FOR LOCALIZATION IN CENTRAL AND PERIPHERAL NEURONS, PARTICULARLY INTRACORTICAL NEURONS OF CEREBRAL-CORTEX
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[7] VASOACTIVE INTESTINAL POLYPEPTIDE IN BRAIN - LOCALIZATION IN AND RELEASE FROM ISOLATED NERVE-TERMINALS
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SAID, SI
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (08) : 3424 - 3428
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HOKFELT, T
ELFVIN, LG
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[J]. NEUROSCIENCE, 1977, 2 (06) : 885 - 896
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