THE SMALL SCARRED KIDNEY IN CHILDHOOD

被引：46

作者：

RISDON, RA

机构：

[1] Department of Histopathology, The Hospital for Sick Children, London, WC1N 3JH, Great Ormond Street

来源：

PEDIATRIC NEPHROLOGY | 1993年 / 7卷 / 04期

关键词：

VESICOURETERAL REFLUX; INTRARENAL REFLUX; REFLUX NEPHROPATHY; RENAL DYSPLASIA;

D O I：

10.1007/BF00857538

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Reflux nephropathy is now a generally accepted term to describe small scarred kidneys discovered during childhood; it recognises the close association between this renal lesion and vesicoureteric reflux (VUR). This paper briefly reviews the pathogenic factors involved in reflux nephropathy and suggests that at least two main mechanisms operate: acquired segmental scarring due to intrarenal reflux and congenital maldevelopment (renal dysplasia). The spectrum of renal changes associated with VUR can be usefully divided on this basis and the opportunity to recognise by fetal ultrasound those renal lesions acquired in utero may further enhance our understanding of the congenital maldevelopment group.

引用

页码：361 / 364

页数：4

共 31 条

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