SEQUENCE OF A LEISHMANIA-MAJOR GENE ENCODING AN UBIQUITIN FUSION PROTEIN

被引：4

作者：

GRAEFF, GR ^{[1
]}

STEELE, PM ^{[1
]}

PETERSON, CL ^{[1
]}

BENNETT, ML ^{[1
]}

LANGER, PJ ^{[1
]}

机构：

[1] UNIV WYOMING,DEPT MOLEC BIOL,LARAMIE,WY 82071

来源：

GENE | 1993年 / 131卷 / 01期

关键词：

POLYUBIQUITIN; PARASITIC PROTOZOA; TRYPANOSOMA; ZINC-BINDING DOMAIN;

D O I：

10.1016/0378-1119(93)90687-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A gene encoding an ubiquitin-tail protein fusion was isolated from the parasitic protozoan, Leishmania major, and sequenced. The L. major tail protein shares 97, 96, 67, 62, 62 and 61% sequence identity with the tail proteins of Trypanosoma brucei, Trypanosoma cruzi, yeast, Dictyostelium discoideum, human, and Arabidopsis thaliana, respectively. The putative 'zinc finger' nucleic acid-binding domain found in all ubiquitin 'tail' or 'extension' proteins described is also conserved in the L. major sequence. The upstream sequence indicated that this gene is not located at the end of a polyubiquitin sequence.

引用

页码：155 / 156

页数：2

共 7 条

[1] THE HUMAN UBIQUITIN-52 AMINO-ACID FUSION PROTEIN GENE SHARES SEVERAL STRUCTURAL FEATURES WITH MAMMALIAN RIBOSOMAL-PROTEIN GENES [J].