INTERACTION OF SODIUM ERYTHROSIN AND POLYVINYLPYRROLIDONE

被引：11

作者：

ANDERSON, JC

BOYCE, GM

机构：

[1] The Research Laboratories, Astra Pharmaceutical Products, Inc, Worcester, Massachusetts

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 11期

关键词：

pH effect—‐erythrosin and erythrosin‐PVP solutions; Polyvinylpyrrolidone; interaction—sodium erythrosin; Spectrophotometry‐quantitation of dye; Stability—erythrosin solutions;

D O I：

10.1002/jps.2600581133

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Sodium erythrosin and polyvinylpyrrolidone (PVP) will form a complex in aqueous solution. The effects of pH and PVP concentration have been investigated and a spectrophotometric method developed for the quantitation of the dye in oxymix, a PVP containing pharmaceutical system. It has also been determined that PVP improves the color stability of an erythrosin solution over a broad pH range. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：1425 / &

共 11 条

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