PHOTOCHEMICAL ADDITION OF AMINO ACIDS TO 14C-URACIL

被引：98

作者：

SMITH, KC

机构：

[1] Department of Radiology, Stanford University School of Medicine, Stanford

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 34卷 / 03期

关键词：

D O I：

10.1016/0006-291X(69)90840-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A survey was performed of the ability of the 22 common amino acids to add photochemically (2537Å) to 14C-uracil. The 11 reactive amino acids were glycine, serine, phenylalanine, tyrosine, tryptophan, cystine, cysteine, methionine, histidine, arginine and lysine. The most reactive amino acids were phenylalanine, tyrosine and cysteine. The relevance of these reactions to the mechanism by which DNA and protein are cross-linked in vivo by ultraviolet light is discussed. © 1969.

引用

页码：354 / &

共 11 条

[1]

SILINI G, 1967, RADIATION RESEARC ED, P756

[2] BIOLOGICAL IMPORTANCE OF ULTRAVIOLET LIGHT INDUCED DNA-PROTEIN CROSSLINKS IN ESCHERICHIA COLI 15 TAU [J].

SMITH, KC ;

HODGKINS, B ;

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[3] THE PHOTOCHEMICAL INTERACTION OF DEOXYRIBONUCLEIC ACID AND PROTEIN INVIVO AND ITS BIOLOGICAL IMPORTANCE [J].

SMITH, KC .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1964, 3 (04) :415-427

[4] A MIXED PHOTOPRODUCT OF URACIL AND CYSTEINE (5-S-CYSTEINE-6-HYDROURACIL) . A POSSIBLE MODEL FOR IN VIVO CROSS-LINKING OF DEOXYRIBONUCLEIC ACID AND PROTEIN BY ULTRAVIOLET LIGHT [J].

SMITH, KC ;

APLIN, RT .

BIOCHEMISTRY, 1966, 5 (06) :2125-&

[5] PHOTOINDUCED DNA-PROTEIN CROSS-LINKS AND BACTERIAL KILLING - A CORRELATION AT LOW TEMPERATURES [J].

SMITH, KC ;

OLEARY, ME .

SCIENCE, 1967, 155 (3765) :1024-&

[6] BIOLOGICAL IMPORTANCE OF U.V.-INDUCED DNA-PROTEIN CROSS-LINKING IN VIVO AND ITS PROBABLE CHEMICAL MECHANISM [J].

SMITH, KC .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1968, 7 (06) :651-&

[7] KINETICS OF PHOTOCHEMICAL ADDITION OF [35S]CYSTEINE TO POLYNUCLEOTIDES AND NUCLEIC ACIDS [J].

SMITH, KC ;

MEUN, DHC .

BIOCHEMISTRY, 1968, 7 (03) :1033-&

[8] DOSE DEPENDENT DECREASE IN EXTRACTABILITY OF DNA FROM BACTERIA FOLLOWING IRRADIATION WITH ULTRAVIOLET LIGHT OR WITH VISIBLE LIGHT PLUS DYE [J].

SMITH, KC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1962, 8 (03) :157-&

[9]

SMITH KC, 1967, RADIAT RES, P756

[10]

SMITH KC, IN PRESS A A

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