MAPPING OF THE MOUSE 86-KDA HEAT-SHOCK PROTEIN EXPRESSED GENE (HSP86-1) ON CHROMOSOME 12 AND RELATED GENES ON CHROMOSOMES 3, 4, 9, AND 11

被引：20

作者：

MOORE, SK ^{[1
]}

APPELLA, E ^{[1
]}

VILLAR, CJ ^{[1
]}

KOZAK, CA ^{[1
]}

机构：

[1] NIAID,MOLEC BIOL LAB,BETHESDA,MD 20892

来源：

GENOMICS | 1991年 / 10卷 / 04期

关键词：

D O I：

10.1016/0888-7543(91)90193-I

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The HSP86 gene family in BALB c, AKR J, C58 J, and NFS N inbred mice comprises an intron-containing expressed gene and, depending on the strain, two to four other HSP86-related members that are apparently processed pseudogenes. The expressed gene locus, Hsp86-1, was identified by its sequence identity with the mouse HSP86 cDNA coding region together with the presence of an intron at the same position as in the homologous human gene. Hsp86-1 was mapped 11.6 cM from the immunoglobulin heavy chain gene Igh on Chromosome 12 using an intersubspecies backcross. Two of the other loci that were common to all inbred strains tested, designated Hsp86-psl and Hsp86-ps2, were mapped to positions on Chromosomes 11 and 3, respectively. An HSP86-related locus specific to NFS N and C58 J mice, designated Hsp86-ps3, was mapped on Chromosome 9. Also, an HSP86-related locus that was unique to NFS N mice, designated Hsp86-ps4, was mapped to Chromosome 4. © 1991.

引用

页码：1019 / 1029

页数：11

共 69 条

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