DNA REARRANGEMENTS AND PHENOTYPIC SWITCHING IN PROKARYOTES

被引：130

作者：

DYBVIG, K ^{[1
]}

机构：

[1] UNIV ALABAMA,DEPT MICROBIOL,BIRMINGHAM,AL 35294

来源：

MOLECULAR MICROBIOLOGY | 1993年 / 10卷 / 03期

关键词：

D O I：

10.1111/j.1365-2958.1993.tb00919.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microorganisms have numerous strategies for coping with environmental changes. In many systems, a single cell has the capacity to generate a seemingly infinite array of phenotypic variants in just a few generations of growth. The resulting heterogeneous population is well equipped for sudden environmental change; even if only a few cells in the population possess a phenotype needed for survival, these cells have the capacity to regenerate a similarly diverse population. Phenotypic switching in these systems usually results from high-frequency DNA rearrangements which are the subject of this review.

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页码：465 / 471

页数：7

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