A general synthesis of mono- and disubstituted 1,4,7-triazacyclononanes

被引：35

作者：

Kovacs, Z ^{[1
]}

Sherry, AD ^{[1
]}

机构：

[1] UNIV TEXAS,DEPT CHEM,RICHARDSON,TX 75083

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 51期

关键词：

D O I：

10.1016/0040-4039(95)02009-E

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,4,7-Triazacyclononane reacts selectively with 2-(t-butoxycarbonyloximino)- and 2-(benzyloxycarbonyloxyimino)-2-phenylacetonitrile to give 1,4-diprotected derivatives which could be converted to mono and disubstituted triazacyclononanes.

引用

页码：9269 / 9272

页数：4

共 7 条

[1]

BRADSHAW JS, 1993, AZA CROWN MACROCYCLE, V51

[2]

ITOH M, 1975, TETRAHEDRON LETT, P4393

[3] APPROACHES TO THE SYNTHESIS OF ENDOTHIOPEPTIDES - SYNTHESIS OF A THIOAMIDE-CONTAINING C-TERMINAL BOMBESIN NONAPEPTIDE [J].

JURAYJ, J ;

CUSHMAN, M .

TETRAHEDRON, 1992, 48 (40) :8601-8614

[4] A GENERAL-SYNTHESIS OF 1,7-DISUBSTITUTED 1,4,7,10-TETRAAZACYCLODODECANES [J].

KOVACS, Z ;

SHERRY, AD .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (02) :185-186

[5] NOTPME - A P-31 NMR PROBE FOR MEASUREMENT OF DIVALENT-CATIONS IN BIOLOGICAL-SYSTEMS [J].

RAMASAMY, R ;

LAZAR, I ;

BRUCHER, E ;

SHERRY, AD ;

MALLOY, CR .

FEBS LETTERS, 1991, 280 (01) :121-124

[6] MODEL STUDIES RELATED TO HEMERYTHRIN - SYNTHESIS AND CHARACTERIZATION OF A BRIDGED TETRANUCLEAR IRON(III) COMPLEX [J].

SESSLER, JL ;

SIBERT, JW ;

LYNCH, V .

INORGANIC CHEMISTRY, 1990, 29 (20) :4143-4146

[7] SELECTIVE N-PROTECTION OF MEDIUM-RING TRIAMINES [J].

WEISMAN, GR ;

VACHON, DJ ;

JOHNSON, VB ;

GRONBECK, DA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (12) :886-887

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