FRUCTOSE TRANSPORT BY ESCHERICHIA-COLI

被引：19

作者：

KORNBERG, HL

机构：

[1] Department of Biochemistry, University of Cambridge

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES | 1990年 / 326卷 / 1236期

关键词：

D O I：

10.1098/rstb.1990.0028

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The utilization of fructose by Escherichia coli involves, as first step, the uptake of the sugar, normally via the phosphoenolpyruvate-dependent phosphotransferase system (PTS). This fructose-specific PTS differs in several ways from that effecting the uptake of other sugars that also possess the 3,4,5-D-arabino-hexose configuration: these differences are discussed. Mutants that lack the genes ptsI and ptsH, which specify components of the PTS common to most PT-sugars, can mutate further to regain the ability to utilize fructose when this is present in relatively high concentration (i.e. greater than 2 mM) in the medium. Some of the properties of this unusual uptake system is discussed.

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页码：505 / 513

页数：9

相关论文

共 29 条

[1] SEQUENCE HOMOLOGIES BETWEEN PROTEINS OF BACTERIAL PHOSPHOENOLPYRUVATE-DEPENDENT SUGAR PHOSPHOTRANSFERASE SYSTEMS - IDENTIFICATION OF POSSIBLE PHOSPHATE-CARRYING HISTIDINE-RESIDUES [J].

BRAMLEY, HF ;

KORNBERG, HL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (14) :4777-4780

[2] GENETIC EXPRESSION OF ENZYME-I-STAR ACTIVITY OF THE PHOSPHOENOLPYRUVATE - SUGAR PHOSPHOTRANSFERASE SYSTEM IN PTSHI DELETION STRAINS OF SALMONELLA-TYPHIMURIUM [J].

CHIN, AM ;

SUTRINA, S ;

FELDHEIM, DA ;

SAIER, MH .

JOURNAL OF BACTERIOLOGY, 1987, 169 (02) :894-896

[3] ROLE OF FRUCTOSE-1,6-DIPHOSPHATASE IN FRUCTOSE UTILIZATION BY ESCHERICHIA-COLI [J].

FERENCI, T ;

KORNBERG, HL .

FEBS LETTERS, 1971, 14 (05) :360-&

[4] ROLE OF PHOSPHOTRANSFERASE-MEDIATED SYNTHESES OF FRUCTOSE 1-PHOSPHATE AND FRUCTOSE 6-PHOSPHATE IN GROWTH OF ESCHERICHIA-COLI ON FRUCTOSE [J].

FERENCI, T ;

KORNBERG, HL .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1974, 187 (1087) :105-119

[5]

FRAENKEL DG, 1968, J BIOL CHEM, V243, P6458

[6] THE PEP - FRUCTOSE PHOSPHOTRANSFERASE SYSTEM IN SALMONELLA-TYPHIMURIUM - FPR COMBINES ENZYME IIIFRU AND PSEUDO-HPR ACTIVITIES [J].

GEERSE, RH ;

IZZO, F ;

POSTMA, PW .

MOLECULAR & GENERAL GENETICS, 1989, 216 (2-3) :517-525

[7] RELATIONSHIP BETWEEN PSEUDO-HPR AND THE PEP - FRUCTOSE PHOSPHOTRANSFERASE SYSTEM IN SALMONELLA-TYPHIMURIUM AND ESCHERICHIA-COLI [J].

GEERSE, RH ;

RUIG, CR ;

SCHUITEMA, ARJ ;

POSTMA, PW .

MOLECULAR & GENERAL GENETICS, 1986, 203 (03) :435-444

[8] THE ROLES OF HPR AND FPR IN THE UTILIZATION OF FRUCTOSE BY ESCHERICHIA-COLI [J].

KORNBERG, H .

FEBS LETTERS, 1986, 194 (01) :12-15

[9] ROLE OF PHOSPHOFRUCTOKINASE IN UTILIZATION OF GLUCOSE BY ESCHERICHIA-COLI [J].

KORNBERG, HL ;

SMITH, J .

NATURE, 1970, 227 (5253) :44-&

[10]

KORNBERG HL, 1987, J GEN MICROBIOL, V133, P341