RECOMBINING THE STRUCTURES OF HIV INTEGRASE, RUVC AND RNASE-H

被引：216

作者：

YANG, W ^{[1
]}

STEITZ, TA ^{[1
]}

机构：

[1] YALE UNIV, HOWARD HUGHES MED INST, DEPT CHEM, NEW HAVEN, CT 06520 USA

来源：

STRUCTURE | 1995年 / 3卷 / 02期

关键词：

D O I：

10.1016/S0969-2126(01)00142-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recently reported crystal structures of two recombination enzymes, the catalytic domain of HIV integrase and Escherichia coli RuvC, an endonuclease, are surprisingly similar to that of ribonuclease H suggesting the possibility that they have a common enzymatic mechanism.

引用

页码：131 / 134

页数：4

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