SPONTANEOUS INTERICTAL SPIKING IN THE AWAKE KINDLED RAT

被引:28
作者
FITZ, JG
MCNAMARA, JO
机构
[1] DUKE UNIV, MED CTR, CTR EPILEPSY, DEPT MED NEUROL, DURHAM, NC 27710 USA
[2] VET ADM HOSP, DURHAM, NC 27705 USA
来源
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1979年 / 47卷 / 05期
关键词
D O I
10.1016/0013-4694(79)90260-8
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The spontaneous interictal spike (SIS) noted in EEG recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. The study provides a detailed, quantitative, temporal and spatial profile of SIS in the amygdaloid kindled rat. The reproducible nature of the development and decline of SIS in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate SIS.
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页码:592 / 596
页数:5
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