ENGINEERED METALLOREGULATION IN ENZYMES

被引:101
作者
HIGAKI, JN [1 ]
FLETTERICK, RJ [1 ]
CRAIK, CS [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143
关键词
D O I
10.1016/0968-0004(92)90245-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Protein engineering of metal-dependent enzyme activity is now possible due to the wealth of information available about metalloproteins. The results emerging from these studies provide insight into our understanding of the chemistry of metals in macromolecular environments as well as the biology of metal-protein interactions.
引用
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页码:100 / 104
页数:5
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