REPEATED DNA IN PNEUMOCYSTIS-CARINII

被引：46

作者：

STRINGER, SL ^{[1
]}

HONG, ST ^{[1
]}

GIUNTOLI, D ^{[1
]}

STRINGER, JR ^{[1
]}

机构：

[1] UNIV CINCINNATI, COLL MED, DEPT MOLEC GENET BIOCHEM & MICROBIOL, CINCINNATI, OH 45267 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1991年 / 29卷 / 06期

关键词：

D O I：

10.1128/JCM.29.6.1194-1201.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A 16-kb DNA fragment designated Rp3-1 and cloned from the genome of rat-derived Pneumocystis carinii was found to contain sequences that were repeated approximately 70 times per genome. The repeated sequences in Rp3-1 spanned at least 10.4 kb. Sequences in Rp3-1 were present on each of the 16 P. carinii chromosomes resolved by field inversion gel electrophoresis. Most of the P. carinii genomic sequences homologous to those in the Rp3-1 clone appeared to be as long as those in the Rp3-1 clone but were highly polymorphic with respect to restriction enzyme cleavage sites. The Rp3-1 DNA fragment appears to be a member of a family of large, degenerate, dispersed repeats.

引用

页码：1194 / 1201

页数：8

共 34 条

[1] MOLECULAR DESCRIPTION OF TELOMERIC HETEROCHROMATIN IN SECALE SPECIES
BEDBROOK, JR
JONES, J
ODELL, M
THOMPSON, RD
FLAVELL, RB
[J]. CELL, 1980, 19 (02) : 545 - 560
[2] THE MOLECULAR-STRUCTURE OF CENTROMERES AND TELOMERES
BLACKBURN, EH
SZOSTAK, JW
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1984, 53 : 163 - 194
[3] TY ELEMENTS TRANSPOSE THROUGH AN RNA INTERMEDIATE
BOEKE, JD
GARFINKEL, DJ
STYLES, CA
FINK, GR
[J]. CELL, 1985, 40 (03) : 491 - 500
[4] EVIDENCE FOR TRANSPOSITION OF DISPERSED REPETITIVE DNA FAMILIES IN YEAST
CAMERON, JR
LOH, EY
DAVIS, RW
[J]. CELL, 1979, 16 (04) : 739 - 751
[5] ELECTROPHORETIC SEPARATIONS OF LARGE DNA-MOLECULES BY PERIODIC INVERSION OF THE ELECTRIC-FIELD
CARLE, GF
FRANK, M
OLSON, MV
[J]. SCIENCE, 1986, 232 (4746) : 65 - 68
[6] CUSHION MT, 1988, LAB INVEST, V58, P324
[7] TRANSFER OF YEAST TELOMERES TO LINEAR PLASMIDS BY RECOMBINATION
DUNN, B
SZAUTER, P
PARDUE, ML
SZOSTAK, JW
[J]. CELL, 1984, 39 (01) : 191 - 201
[8] RIBOSOMAL-RNA SEQUENCE SHOWS PNEUMOCYSTIS-CARINII TO BE A MEMBER OF THE FUNGI
EDMAN, JC
KOVACS, JA
MASUR, H
SANTI, DV
ELWOOD, HJ
SOGIN, ML
[J]. NATURE, 1988, 334 (6182) : 519 - 522
[9] ISOLATION AND EXPRESSION OF THE PNEUMOCYSTIS-CARINII THYMIDYLATE SYNTHASE GENE
EDMAN, U
EDMAN, JC
LUNDGREN, B
SANTI, DV
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (17) : 6503 - 6507
[10] HABER JE, 1983, MOBILE GENETIC ELEME, P559

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