IMMUNOHISTOCHEMICAL CHARACTERISTICS OF POLYMYOSITIS IN PATIENTS WITH HTLV-I-ASSOCIATED MYELOPATHY AND HTLV-I CARRIERS

被引：26

作者：

HIGUCHI, I ^{[1
]}

MONTEMAYOR, ES ^{[1
]}

IZUMO, S ^{[1
]}

INOSE, M ^{[1
]}

OSAME, M ^{[1
]}

机构：

[1] UNIV PHILIPPINES,PHILIPPINE GEN HOSP,DEPT MED,MANILA,PHILIPPINES

来源：

MUSCLE & NERVE | 1993年 / 16卷 / 05期

关键词：

POLYMYOSITIS; HTLV-I; MHC CLASS-I; MHC CLASS-II; ADHESION MOLECULE;

D O I：

10.1002/mus.880160507

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The immunohistochemical characteristics of polymyositis in patients with HTLV-I-associated myelopathy (HAM) and HTLV-I carriers were studied. Infiltrating cells were predominantly T cells and were not different from in the control group. All specimens contained positively staining muscle fibers for MHC class I antigens, but class II antigens were also expressed in some muscle fibers in 1 patient with HTLV-I-negative polymyositis, 3 patients with HTLV-I-positive polymyositis, and all 5 HAM patients with polymyositis. Expression of the neural cell adhesion molecule was lowest in the HAM patients. These findings may suggest a different immune environment in polymyositis with HAM.

引用

页码：472 / 476

页数：5

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