DESIGN OF THE EPC-9, A COMPUTER-CONTROLLED PATCH-CLAMP AMPLIFIER .1. HARDWARE

被引：24

作者：

SIGWORTH, FJ

机构：

[1] Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510

来源：

JOURNAL OF NEUROSCIENCE METHODS | 1995年 / 56卷 / 02期

关键词：

PATCH DAMP; ION CHANNEL; COMPUTER; ELECTROPHYSIOLOGY; DATA ACQUISITION;

D O I：

10.1016/0165-0270(94)00128-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The EPC-9 patch-clamp amplifier is a digitally controlled analog device for recording currents in membrane patches and in small cells. It has neither front-panel controls nor internal trim adjustments; instead all gain, range-changing, transient cancellation, calibration and other functions are computer controlled. Novel aspects of the circuit design of this instrument are discussed, with special reference to the issues of allowing computer control of all functions.

引用

页码：195 / 202

页数：8

共 5 条

[1] SUPERCHARGING - A METHOD FOR IMPROVING PATCH-CLAMP PERFORMANCE [J].