GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND HISTOGENESIS OF EPIDERMOID CARCINOMA OF CERVIX

被引:30
作者
PARK, IJ
JONES, HW
机构
[1] Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine Baltimore, MD
关键词
D O I
10.1016/0002-9378(68)90439-0
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The result of vertical starch gel electrophoresis of blood, cancerous, and noncancerous epithelium of the cervix of 18 patients who were heterozygous for G-6-PD variants is presented. Among 10 patients without cancer of the cervix, examination of the cervical epithelium showed 9 with 2 bands and one with 1 band. Among 8 patients with cancer, examination of the cancer tissue showed 5 with a single band (1A and 4B) and 3 with double bands. It is proposed that the evidence is consistent with the concept that epidermoid carcinoma of the cervix arises from a single cell. It is also concluded that the Lyon phenomenon is also functioning in at least some tumors. © 1968.
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页码:106 / &
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