REACTIONS OF CYSTEINE, ITS DERIVATIVES, GLUTATHIONE, COENZYME-A, AND DIHYDROLIPOIC ACID WITH ISOTHIOCYANATES

被引：52

作者：

PODHRADSKY, D ^{[1
]}

DROBNICA, L ^{[1
]}

KRISTIAN, P ^{[1
]}

机构：

[1] SLOVAK UNIV TECHNOL BRATISLAVA, DEPT MICROBIOL & BIOCHEM, CS-88037 BRATISLAVA, CZECHOSLOVAKIA

来源：

EXPERIENTIA | 1979年 / 35卷 / 02期

关键词：

D O I：

10.1007/BF01920581

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Isothiocyanates react with deprotonated SH groups of investigated compounds to give the esters of N-monosubstituted dithiocarbamic acid. In the presence of the SH and NH2 groups (Cys, GSH), isothiocyanates react primarily with the SH groups. The reactions are dependent on the pKaSH values. © 1979 Birkhäuser Verlag.

引用

页码：154 / 155

页数：2

共 14 条

[1]

ANTOS K, 1965, CHEM ZVESTI, V19, P353

[2] THE ACID STRENGTH OF THE -SH GROUP IN CYSTEINE AND RELATED COMPOUNDS [J].

BENESCH, RE ;

BENESCH, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (22) :5877-5881

[3] DETERMINATION OF MICROSCOPIC IONIZATION CONSTANTS OF CYSTEINE [J].

CLEMENT, GE ;

HARTZ, TP .

JOURNAL OF CHEMICAL EDUCATION, 1971, 48 (06) :395-&

[4] ACIDIC DISSOCIATION CONSTANTS OF THIOLS [J].

DANEHY, JP ;

PARAMESW.KN .

JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1968, 13 (03) :386-&

[5]

DROBINIC.L, 1965, COLLECT CZECH CHEM C, V30, P1618

[6]

DROBNICA L, 1965, COLLECT CZECH CHEM C, V30, P1221

[7]

DROBNICA L, 1965, COLLECT CZECH CHEM C, V30, P99

[8]

DROBNICA L, 1975, COLLECT CZECH CHEM C, V40, P3688

[9] The inhibitory effect of substituents in chemical reactions Part I The reactivity of the amino-group in substituted arylamines [J].

Dyson, GM ;

George, HJ ;

Hunter, RF .

JOURNAL OF THE CHEMICAL SOCIETY, 1927, :436-445

[10]

Jocelyn P.C., 1972, BIOCH SH GROUP, P52

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