ACUTE EFFECTS OF HYDROCORTISONE ON THE REABSORPTION OF INORGANIC-PHOSPHATE IN NORMAL, ADRENALECTOMIZED AND PARATHYROIDECTOMIZED RATS

被引：14

作者：

FRICK, A

DURASIN, I

机构：

[1] Physiologisches Institut der Universität München, München 2, D-8000

来源：

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 1979年 / 382卷 / 02期

关键词：

Adrenalectomy; Hydrocortisone; Kidney; Parathyroid hormone; Sodium transport; Transport of inorganic phosphate;

D O I：

10.1007/BF00584212

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Clearance studies have been performed in order to examine the acute effects of hydrocortisone on the reabsorption of inorganic phosphate (Pi) in normal, acutely adrenalectomized (Adr. X) and acutely parathyroidectomized (PTX) rats. Hydrocortisone increased the glomerular filtration rates in all groups, normalized the capacity to excrete water in the Adr. X animals, did not change consistently the fractional reabsorption of sodium in all series and diminished the fractional reabsorption of inorganic phosphate in Adr. X rats from 91.4±6.5 (mean ±S.D.) to 78.2±8.5% (P<0.001). It is concluded that the decrease of the fractional reabsorption of Pi in the Adr. X animals was rather the result of the increased filtered load than a direct effect of hydrocortisone on the Pi transport. © 1979 Springer-Verlag.

引用

页码：123 / 126

页数：4

共 12 条

[1] ADRENAL-CORTEX AND KIDNEY [J].