VIRIDANS STREPTOCOCCAL BACTEREMIA IN PATIENTS WITH NEUTROPENIA

被引：77

作者：

RICHARD, P

DELVALLE, GA

MOREAU, P

MILPIED, N

FELICE, MP

DAESCHLER, T

HAROUSSEAU, JL

RICHET, H

机构：

[1] HOP HOTEL DIEU,FAC CHIRURG DENT,F-44035 NANTES,FRANCE

[2] HOP HOTEL DIEU,SERV HEMATOL,F-44035 NANTES,FRANCE

来源：

LANCET | 1995年 / 345卷 / 8965期

关键词：

D O I：

10.1016/S0140-6736(95)90117-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Viridans streptococcal bacteraemia is frequent in neutropenic patients. 25 neutropenic patients with viridans streptococcal bacteraemia were compared with 64 control patients. Exposure to repeated chemotherapy or cytarabine were independent risk-factors for streptococcal bacteraemia. The use of carboxyureidopenicillins and stay in laminar-airflow rooms were protective. In a further cohort study of 49 patients, oral streptococci with the same ribotype as blood isolates were recovered from all 7 bacteraemic patients. The oral cavity is a portal of entry for viridans streptococci bacteraemia in neutropenic patients, especially after oral mucosal damage induced by repeated chemotherapy.

引用

页码：1607 / 1609

页数：3

共 9 条

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