SYNTHESIS OF 7-MEMBERED, 8-MEMBERED AND 9-MEMBERED RINGS VIA ENDO HECK CYCLIZATIONS OF AMINO-ACID DERIVED SUBSTRATES

被引：50

作者：

GIBSON, SE

MIDDLETON, RJ

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 17期

关键词：

D O I：

10.1039/c39950001743

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Aryl iodides tethered to dehydroalanine units by two to four methylene groups undergo intramolecular Heck reactions under anhydrous Jeffery conditions to give 7-, 8- and 9-membered rings by the endo-mode of cyclisation; under harsher; conditions, a palladium intermediate formed by the exo-mode of cyclisation is expressed as reduced products.

引用

页码：1743 / 1744

页数：2

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