EFFECTS OF CIMETIDINE ON HEALING OF CHRONIC GASTRIC AND DUODENAL ULCERS IN DOGS

被引：10

作者：

OKABE, S ^{[1
]}

TAKEUCHI, K ^{[1
]}

MURATA, T ^{[1
]}

URUSHIDANI, T ^{[1
]}

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,DEPT CHEM PHARMACOL,TOKYO 113,JAPAN

来源：

AMERICAN JOURNAL OF DIGESTIVE DISEASES | 1978年 / 23卷 / 02期

关键词：

D O I：

10.1007/BF01073194

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The effects of cimetidine on healing of gastric and duodenal ulcers induced in mongrel dogs were studied. Gastric ulcers were produced by subserosal injection of acetic acid solution and duodenal ulcers by topical application of acetic acid on the serosal surface of the duodenum. Oral treatment with cimetidine, 450 mg/dog/day in three divided doses for 14 days, produced a remarkable acceleration of healing of duodenal ulcers but exerted little influence on gastric ulcers. © 1978 Digestive Disease Systems, Inc.

引用

页码：166 / 168

页数：3

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