TOTAL SYNTHESIS OF O-METHYLFLAVINANTINE

被引：41

作者：

KAMETANI, T

FUKUMOTO, K

SATOH, F

YAGI, H

机构：

[1] Pharmaceutical Institute, School of Medicine, Tohoku University, Sendai, No. 85, Kitayobancho

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 04期

关键词：

D O I：

10.1039/j39690000520

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The diazotisation of 6,7-dimethoxy- and 7-ethoxy-6-methoxy-1-(2-amino-4,5- dimethoxybenzyl)-1,2,3,4-tetrahydro-2-methylisoquinoline (XIII) and (XVIII), followed by thermal decomposition of the resulting diazonium salt, gave O-methylflavinantine (VI), whose synthesis has proved structure (IV) for flavinantine to be correct.

引用

页码：520 / &

共 18 条

[1] PHENOL OXIDATION AND BIOSYNTHESIS .12. STEREOCHEMICAL STUDIES RELATED TO BIOSYNTHESIS OF MORPHINE ALKALOIDS
BARTON, DHR
BHAKUNI, DS
JAMES, R
KIRBY, GW
[J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1967, (02): : 128 - &
[2] INVESTIGATIONS ON BIOSYNTHESIS OF MORPHINE ALKALOIDS
BARTON, DHR
KIRBY, GW
STEGLICH, W
THOMAS, GM
BATTERSBY, AR
DOBSON, TA
RAMUZ, H
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1965, (APR): : 2423 - +
[3] BARTON DHR, 1957, FESTSCHRIFT ARTHUR S, P114
[4] SYNTHESES ALONG BIOSYNTHETIC PATHWAYS .I. SYNTHESIS OF (+)-ISOTHEBAINE
BATTERSBY, AR
BROWN, TH
CLEMENTS, JH
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1965, (AUG): : 4550 - +
[5] SYNTHESIS OF PROTOSTEPHANINE BY A ROUTE RELATED TO BIOSYNTHETIC PATHWAY
BATTERSBY, AR
BHATNAGAR, AK
HACKETT, P
THORNBER, CW
STAUNTON, J
[J]. CHEMICAL COMMUNICATIONS, 1968, (20) : 1214 - +
[6] FLAVINANTINE AND FLAVININE NOVEL MORPHINANDIENONE ALKALOIDS FROM CROTON FLAVENS L
CHAMBERS, C
STUART, KL
[J]. CHEMICAL COMMUNICATIONS, 1968, (06) : 328 - &
[7] DeTar D. F., 1957, ORG REACT, V9, P409
[8] STRUCTURES OF AMURINE AND NUDAURINE
DOPKE, W
FLENTJE, H
JEFFS, PW
[J]. TETRAHEDRON, 1968, 24 (12) : 4459 - &
[9] FALTIS F, 1951, ARCH PHARM, V284, P281
[10] Gadamer J., 1911, ARCH PHARM, V249, P680

← 1 2 →