DIRECT RADIOIMMUNOASSAY OF ESTROGEN GLUCURONIDES IN HUMAN FEMALE URINE

被引:80
作者
BAKER, TS [1 ]
JENNISON, KM [1 ]
KELLIE, AE [1 ]
机构
[1] MIDDLESEX HOSP,SCH MED,ACAD DEPT OBSTET & GYNAECOL,LONDON W1P 5PR,ENGLAND
关键词
D O I
10.1042/bj1770729
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Radioimmunoassays for five oestrogen metabolites in urine are described; they are oestrone 3-glucuronide, oestradiol 3-glucuronide, oestradiol 17β-glucuronide, oestriol 3-glucuronide and oestriol 16α-glucuronide. These assays have proved accurate and reliable and can be performed rapidly; they have been carried out directly in diluted menstrual-cycle urine and pregnancy urine. No sample pretreatment was required. Preliminary results suggest that clinically useful information can be obtained by performing these assays on random urine specimens.
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页码:729 / 738
页数:10
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