ENHANCEMENT OF CELL-GROWTH ON GROWTH FACTOR-IMMOBILIZED POLYMER FILM

被引：112

作者：

ITO, Y ^{[1
]}

LIU, SQ ^{[1
]}

IMANISHI, Y ^{[1
]}

机构：

[1] KYOTO UNIV,FAC ENGN,DEPT POLYMER CHEM,SAKYO KU,KYOTO 606,JAPAN

来源：

BIOMATERIALS | 1991年 / 12卷 / 05期

关键词：

CELL GROWTH; POLYMERS; GROWTH FACTORS; SURFACE TREATMENT;

D O I：

10.1016/0142-9612(91)90141-V

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Insulin, transferrin and collagen were immobilized on the surface of hydrolysed poly(methyl methacrylate) films. Mouse STO fibroblasts were cultured on the protein-immobilized films. Growth factors remained immobilized without detachment and accelerated cell growth in a more potent manner than free or adsorbed growth factors. Immobilized collagen enhanced the flattening of adhered cells in the early stages of cell adhesion, but did not enhance cell growth significantly.

引用

页码：449 / 453

页数：5

共 14 条

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