GABA AS AN INHIBITORY TRANSMITTER IN THE PIGEON ISTHMO-TECTAL PATHWAY

被引：22

作者：

FELIX, D ^{[1
]}

WU, GY ^{[1
]}

WANG, SR ^{[1
]}

机构：

[1] ACAD SINICA,INST BIOPHYS,VISUAL INFORMAT PROC LAB,100101 BEIJING,PEOPLES R CHINA

来源：

NEUROSCIENCE LETTERS | 1994年 / 169卷 / 1-2期

基金：

中国国家自然科学基金;

关键词：

PIGEON; NUCLEUS ISTHMUS; ISTHMO-TECTAL PATHWAY; OPTIC TECTUM; MICROIONTOPHORESIS; GAMMA-AMINOBUTYRIC ACID; BICUCULLINE;

D O I：

10.1016/0304-3940(94)90394-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the present investigation, the effects of inhibitory amino acids and their antagonists were tested on isthmo-tectal projection in the pigeon. The majority of superficial tectal cells are inhibited following stimulation of the parvocellular division of nucleus isthmi. A smaller portion of tectal cells showed excitatory responses followed by an inhibitory period. Both inhibitory mechanisms are blocked by the specific gamma-aminobutyric acid (GABA)-antagonist bicuculline but not by strychnine. Our results support the idea that GABA acts as an inhibitory neurotransmitter in the pigeon isthmo-tectal pathways.

引用

页码：212 / 214

页数：3

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