ADPASE ACTIVITY IN HUMAN MATERNAL AND CORD BLOOD - POSSIBLE EVIDENCE FOR A PLACENTA-SPECIFIC VASCULAR PROTECTIVE MECHANISM

被引：11

作者：

BARRADAS, MA

MIKHAILIDIS, DP

DANDONA, P

机构：

[1] ROYAL FREE HOSP,DEPT CHEM PATHOL & HUMAN METAB,METAB UNIT,LONDON NW3 2QG,ENGLAND

[2] UNIV LONDON,LONDON,ENGLAND

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1990年 / 31卷 / 01期

关键词：

ADPase; Placenta; Platelet aggregation; Pregnancy; Umbilical cord;

D O I：

10.1016/0020-7292(90)90175-K

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

ADPase enzyme activity was assessed in maternal and cord plasma by adding radio-labelled ADP and quantitating the degradation products. Cord plasma had sufficiently greater ADPase activity than the corresponding maternal plasma obtained ante- and post-partum. Thus, residual radiolabelled ADP was 30, 32 and 17% of total radioactivity after 30 min incubation (37°C) in maternal ante-partum, maternal post-partum and cord plasmas, respectively. ADPase may act as a platelet aggregation inhibitor in the placental and fetal circulation. © 1990.

引用

页码：15 / 20

页数：6

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