SYNTHESIS OF TRICYCLIC COMPOUNDS WITH SULFUR AND SILICON HETEROATOMS IN THE CENTRAL RING

The synthesis of tricyclic derivatives which contain both silicon and sulfur in a central six-, seven- and eight-membered ring are described. Phenothiasilin-5,5-dioxides are prepared by treatment of (o-LiC6H4)2SO2 with dichlorosilanes. Reduction of the sulfone group is described as well as attempts to introduce aminopropyl substituents at silicon. Thiasilepins are prepared from the Grignard reagent of (o-BrC6H4CH2SC6H4Br-o) and reactions of this ring system are described. Reaction of Me2Si(C6H4CH2Br-o) with Na2S gave a thiasilocin derivative. © 1979.