NUTRITIONAL MANIPULATIONS AND TUMOR-GROWTH .2. EFFECTS OF INTRAVENOUS-FEEDING

被引：44

作者：

GOODGAME, JT ^{[1
]}

LOWRY, SF ^{[1
]}

BRENNAN, MF ^{[1
]}

机构：

[1] NCI,SURG BRANCH,SURG METAB SECT,BETHESDA,MD 20205

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 1979年 / 32卷 / 11期

关键词：

D O I：

10.1093/ajcn/32.11.2285

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The effects of acute parental nutritional manipulations on tumor and carcass growth were examined in the rat. Carcass mass was maintained in animals fed diets either orally or intravenously. Reduction in liver incorporation of tritiated methyl thymidine and increases in liver fat content in the total parental nutrition groups indicated that the high carbohydrate, high nitrogen, intravenous diet was less than optimal. Tumor growth as measured by changes in volume, weight, DNA content, or nitrogen content was unaffected by the various nutritional regimens. Tumor dpm/μg DNA was reduced by those intravenous regimens that were associated with hyperglycemia. Host carcass weight, can be maintained with intravenous nutrition, but normal growth is not restored by the current intravenous regimens.

引用

页码：2285 / 2294

页数：10

共 16 条

[1]

BEGG RW, 1951, CANCER RES, V11, P409

[2] STIMULATION OF GROWTH OF A TRANSPLANTABLE HEPATOMA IN RATS BY PARENTERAL NUTRITION [J].