THE MICROTUBULE LATTICE - 20 YEARS ON

被引：43

作者：

AMOS, LA

机构：

[1] MRC Laboratory of Molecular Biology, Cambridge, Hills Road

来源：

TRENDS IN CELL BIOLOGY | 1995年 / 5卷 / 02期

关键词：

D O I：

10.1016/S0962-8924(00)88938-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In 1974, optical diffraction and image analysis indicated that tubulin dimers in the cylindrically complete A-tubule of flagellar doublet microtubules are arranged with helical symmetry, while those in the incomplete B-tubule associate differently. Recently, electron micrographs of reassembled brain microtubules decorated with kinesin heads have shown that the tubulin dimers there are arranged as in the B-tubule. The lack of symmetry of microtubules assembled in vitro prompts Linda Amos to speculate here that the assembly process in vitro may differ from that occurring in the cell.

引用

页码：48 / 51

页数：4

共 17 条

[1]

AMOS LA, 1974, J CELL SCI, V14, P523

[2] ARRANGEMENT OF HIGH MOLECULAR-WEIGHT ASSOCIATED PROTEINS ON PURIFIED MAMMALIAN BRAIN MICROTUBULES [J].