ESTIMATE OF THE MINIMAL FREQUENCY OF CYTOLYTIC LYMPHOCYTE-T EFFECTOR CELLS GENERATED IN ALLOGENEIC REACTIONS

被引：7

作者：

ENGERS, HD

FITCH, FW

机构：

[1] UNIV CHICAGO,FRANKLIN MCLEAN MEM RES INST,CHICAGO,IL 60637

[2] UNIV CHICAGO,DEPT PATHOL,CHICAGO,IL 60637

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1979年 / 25卷 / 01期

关键词：

D O I：

10.1016/0022-1759(79)90159-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A 'micro' modification of the standard 51Cr release assay was developed. With this assay, significant cytolysis was obtained employing 100-200 51Cr-labeled target cells and fewer than 100 lymphocytes obtained from mixed leukocyte cultures. A minimal estimate as to the actual frequency of effector cells was determined for both primary (1 cell in 30) and secondary (1 cell in 8) cytolytic T lymphocyte populations. © 1979.

引用

页码：13 / 20

页数：8

共 19 条

[1] FREQUENCY OF EFFECTOR CELLS IN POPULATIONS CONTAINING CYTOTOXIC T-LYMPHOCYTES [J].