A NEW TRIMETHOPRIM RESISTANCE GENE, DHFRX, IN THE IN7 INTEGRON OF PLASMID PDGO100

被引：50

作者：

PARSONS, Y

HALL, RM

STOKES, HW

机构：

[1] CSIRO, DIV BIOMOLEC ENGN, MOLEC BIOL LAB, POB 184, N RYDE, NSW 2113, AUSTRALIA

[2] MACQUARIE UNIV, SCH BIOL SCI, SYDNEY, NSW 2109, AUSTRALIA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1991年 / 35卷 / 11期

关键词：

D O I：

10.1128/AAC.35.11.2436

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new trimethoprim resistance determinant, designated dhfrX, was identified in the In7 integron of pDGO100. The sequence of the dhfrX dihydrofolate reductase is up to 28% identical to the sequences of several known dihydrofolate reductase proteins. The dhfrX gene is adjacent to the second 3'-conserved segment of the In7 integron, but the first 77 bases of this segment are not present.

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页码：2436 / 2439

页数：4

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