The Conductance of Bile Salt-Lecithin-Water Mixtures

被引：10

作者：

Evans, D. Fennell ^{[1
,2
]}

DePalma, Ralph ^{[1
,2
]}

Nadas, John ^{[1
,2
]}

Thomas, John ^{[1
,2
]}

机构：

[1] Case Western Reserve Univ, Dept Chem, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Dept Surg, Cleveland, OH 44106 USA

来源：

JOURNAL OF SOLUTION CHEMISTRY | 1972年 / 1卷 / 04期

关键词：

Conductance; aqueous solutions; sodium glycodeoxycholate; sodium taurodeoxycholate; lecithin; bile salts; micelles; gallbladder; cholesterol;

D O I：

10.1007/BF00715995

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The conductance of aqueous solutions of sodium glycodeoxycholate and sodium taurodeoxycholate displays a complex concentration dependence (0-0.5 C) with a maximum and minimum occurring in dilute solutions. This behavior can be related to physiologic concentrations observed in hepatic and gallbladder bile and interpreted in terms of anion dimerization and ultimately micellization. The addition of lecithin in 1:2 or 1:5 molar ratios results in micellization at lower concentration, disappearance of the maximum and minimum in the conductance curve, and a decrease in the total conductance.

引用

页码：377 / 386

页数：10

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